- Bipolar Disorder
- Therapy Center
- When To See a Therapist
- Types of Therapy
- Best Online Therapy
- Best Couples Therapy
- Managing Stress
- Sleep and Dreaming
- Understanding Emotions
- Self-Improvement
- Healthy Relationships
- Student Resources
- Personality Types
- Guided Meditations
- Verywell Mind Insights
- 2024 Verywell Mind 25
- Mental Health in the Classroom
- Editorial Process
- Meet Our Review Board
- Crisis Support
How to Write a Great Hypothesis
Hypothesis Definition, Format, Examples, and Tips
Kendra Cherry, MS, is a psychosocial rehabilitation specialist, psychology educator, and author of the "Everything Psychology Book."
Amy Morin, LCSW, is a psychotherapist and international bestselling author. Her books, including "13 Things Mentally Strong People Don't Do," have been translated into more than 40 languages. Her TEDx talk, "The Secret of Becoming Mentally Strong," is one of the most viewed talks of all time.
Verywell / Alex Dos Diaz
- The Scientific Method
Hypothesis Format
Falsifiability of a hypothesis.
- Operationalization
Hypothesis Types
Hypotheses examples.
- Collecting Data
A hypothesis is a tentative statement about the relationship between two or more variables. It is a specific, testable prediction about what you expect to happen in a study. It is a preliminary answer to your question that helps guide the research process.
Consider a study designed to examine the relationship between sleep deprivation and test performance. The hypothesis might be: "This study is designed to assess the hypothesis that sleep-deprived people will perform worse on a test than individuals who are not sleep-deprived."
At a Glance
A hypothesis is crucial to scientific research because it offers a clear direction for what the researchers are looking to find. This allows them to design experiments to test their predictions and add to our scientific knowledge about the world. This article explores how a hypothesis is used in psychology research, how to write a good hypothesis, and the different types of hypotheses you might use.
The Hypothesis in the Scientific Method
In the scientific method , whether it involves research in psychology, biology, or some other area, a hypothesis represents what the researchers think will happen in an experiment. The scientific method involves the following steps:
- Forming a question
- Performing background research
- Creating a hypothesis
- Designing an experiment
- Collecting data
- Analyzing the results
- Drawing conclusions
- Communicating the results
The hypothesis is a prediction, but it involves more than a guess. Most of the time, the hypothesis begins with a question which is then explored through background research. At this point, researchers then begin to develop a testable hypothesis.
Unless you are creating an exploratory study, your hypothesis should always explain what you expect to happen.
In a study exploring the effects of a particular drug, the hypothesis might be that researchers expect the drug to have some type of effect on the symptoms of a specific illness. In psychology, the hypothesis might focus on how a certain aspect of the environment might influence a particular behavior.
Remember, a hypothesis does not have to be correct. While the hypothesis predicts what the researchers expect to see, the goal of the research is to determine whether this guess is right or wrong. When conducting an experiment, researchers might explore numerous factors to determine which ones might contribute to the ultimate outcome.
In many cases, researchers may find that the results of an experiment do not support the original hypothesis. When writing up these results, the researchers might suggest other options that should be explored in future studies.
In many cases, researchers might draw a hypothesis from a specific theory or build on previous research. For example, prior research has shown that stress can impact the immune system. So a researcher might hypothesize: "People with high-stress levels will be more likely to contract a common cold after being exposed to the virus than people who have low-stress levels."
In other instances, researchers might look at commonly held beliefs or folk wisdom. "Birds of a feather flock together" is one example of folk adage that a psychologist might try to investigate. The researcher might pose a specific hypothesis that "People tend to select romantic partners who are similar to them in interests and educational level."
Elements of a Good Hypothesis
So how do you write a good hypothesis? When trying to come up with a hypothesis for your research or experiments, ask yourself the following questions:
- Is your hypothesis based on your research on a topic?
- Can your hypothesis be tested?
- Does your hypothesis include independent and dependent variables?
Before you come up with a specific hypothesis, spend some time doing background research. Once you have completed a literature review, start thinking about potential questions you still have. Pay attention to the discussion section in the journal articles you read . Many authors will suggest questions that still need to be explored.
How to Formulate a Good Hypothesis
To form a hypothesis, you should take these steps:
- Collect as many observations about a topic or problem as you can.
- Evaluate these observations and look for possible causes of the problem.
- Create a list of possible explanations that you might want to explore.
- After you have developed some possible hypotheses, think of ways that you could confirm or disprove each hypothesis through experimentation. This is known as falsifiability.
In the scientific method , falsifiability is an important part of any valid hypothesis. In order to test a claim scientifically, it must be possible that the claim could be proven false.
Students sometimes confuse the idea of falsifiability with the idea that it means that something is false, which is not the case. What falsifiability means is that if something was false, then it is possible to demonstrate that it is false.
One of the hallmarks of pseudoscience is that it makes claims that cannot be refuted or proven false.
The Importance of Operational Definitions
A variable is a factor or element that can be changed and manipulated in ways that are observable and measurable. However, the researcher must also define how the variable will be manipulated and measured in the study.
Operational definitions are specific definitions for all relevant factors in a study. This process helps make vague or ambiguous concepts detailed and measurable.
For example, a researcher might operationally define the variable " test anxiety " as the results of a self-report measure of anxiety experienced during an exam. A "study habits" variable might be defined by the amount of studying that actually occurs as measured by time.
These precise descriptions are important because many things can be measured in various ways. Clearly defining these variables and how they are measured helps ensure that other researchers can replicate your results.
Replicability
One of the basic principles of any type of scientific research is that the results must be replicable.
Replication means repeating an experiment in the same way to produce the same results. By clearly detailing the specifics of how the variables were measured and manipulated, other researchers can better understand the results and repeat the study if needed.
Some variables are more difficult than others to define. For example, how would you operationally define a variable such as aggression ? For obvious ethical reasons, researchers cannot create a situation in which a person behaves aggressively toward others.
To measure this variable, the researcher must devise a measurement that assesses aggressive behavior without harming others. The researcher might utilize a simulated task to measure aggressiveness in this situation.
Hypothesis Checklist
- Does your hypothesis focus on something that you can actually test?
- Does your hypothesis include both an independent and dependent variable?
- Can you manipulate the variables?
- Can your hypothesis be tested without violating ethical standards?
The hypothesis you use will depend on what you are investigating and hoping to find. Some of the main types of hypotheses that you might use include:
- Simple hypothesis : This type of hypothesis suggests there is a relationship between one independent variable and one dependent variable.
- Complex hypothesis : This type suggests a relationship between three or more variables, such as two independent and dependent variables.
- Null hypothesis : This hypothesis suggests no relationship exists between two or more variables.
- Alternative hypothesis : This hypothesis states the opposite of the null hypothesis.
- Statistical hypothesis : This hypothesis uses statistical analysis to evaluate a representative population sample and then generalizes the findings to the larger group.
- Logical hypothesis : This hypothesis assumes a relationship between variables without collecting data or evidence.
A hypothesis often follows a basic format of "If {this happens} then {this will happen}." One way to structure your hypothesis is to describe what will happen to the dependent variable if you change the independent variable .
The basic format might be: "If {these changes are made to a certain independent variable}, then we will observe {a change in a specific dependent variable}."
A few examples of simple hypotheses:
- "Students who eat breakfast will perform better on a math exam than students who do not eat breakfast."
- "Students who experience test anxiety before an English exam will get lower scores than students who do not experience test anxiety."
- "Motorists who talk on the phone while driving will be more likely to make errors on a driving course than those who do not talk on the phone."
- "Children who receive a new reading intervention will have higher reading scores than students who do not receive the intervention."
Examples of a complex hypothesis include:
- "People with high-sugar diets and sedentary activity levels are more likely to develop depression."
- "Younger people who are regularly exposed to green, outdoor areas have better subjective well-being than older adults who have limited exposure to green spaces."
Examples of a null hypothesis include:
- "There is no difference in anxiety levels between people who take St. John's wort supplements and those who do not."
- "There is no difference in scores on a memory recall task between children and adults."
- "There is no difference in aggression levels between children who play first-person shooter games and those who do not."
Examples of an alternative hypothesis:
- "People who take St. John's wort supplements will have less anxiety than those who do not."
- "Adults will perform better on a memory task than children."
- "Children who play first-person shooter games will show higher levels of aggression than children who do not."
Collecting Data on Your Hypothesis
Once a researcher has formed a testable hypothesis, the next step is to select a research design and start collecting data. The research method depends largely on exactly what they are studying. There are two basic types of research methods: descriptive research and experimental research.
Descriptive Research Methods
Descriptive research such as case studies , naturalistic observations , and surveys are often used when conducting an experiment is difficult or impossible. These methods are best used to describe different aspects of a behavior or psychological phenomenon.
Once a researcher has collected data using descriptive methods, a correlational study can examine how the variables are related. This research method might be used to investigate a hypothesis that is difficult to test experimentally.
Experimental Research Methods
Experimental methods are used to demonstrate causal relationships between variables. In an experiment, the researcher systematically manipulates a variable of interest (known as the independent variable) and measures the effect on another variable (known as the dependent variable).
Unlike correlational studies, which can only be used to determine if there is a relationship between two variables, experimental methods can be used to determine the actual nature of the relationship—whether changes in one variable actually cause another to change.
The hypothesis is a critical part of any scientific exploration. It represents what researchers expect to find in a study or experiment. In situations where the hypothesis is unsupported by the research, the research still has value. Such research helps us better understand how different aspects of the natural world relate to one another. It also helps us develop new hypotheses that can then be tested in the future.
Thompson WH, Skau S. On the scope of scientific hypotheses . R Soc Open Sci . 2023;10(8):230607. doi:10.1098/rsos.230607
Taran S, Adhikari NKJ, Fan E. Falsifiability in medicine: what clinicians can learn from Karl Popper [published correction appears in Intensive Care Med. 2021 Jun 17;:]. Intensive Care Med . 2021;47(9):1054-1056. doi:10.1007/s00134-021-06432-z
Eyler AA. Research Methods for Public Health . 1st ed. Springer Publishing Company; 2020. doi:10.1891/9780826182067.0004
Nosek BA, Errington TM. What is replication ? PLoS Biol . 2020;18(3):e3000691. doi:10.1371/journal.pbio.3000691
Aggarwal R, Ranganathan P. Study designs: Part 2 - Descriptive studies . Perspect Clin Res . 2019;10(1):34-36. doi:10.4103/picr.PICR_154_18
Nevid J. Psychology: Concepts and Applications. Wadworth, 2013.
By Kendra Cherry, MSEd Kendra Cherry, MS, is a psychosocial rehabilitation specialist, psychology educator, and author of the "Everything Psychology Book."
Work With Us
Private Coaching
Done-For-You
Short Courses
Client Reviews
Free Resources
What Is A Research Hypothesis?
A Plain-Language Explainer + Practical Examples
Research Hypothesis 101
- What is a hypothesis ?
- What is a research hypothesis (scientific hypothesis)?
- Requirements for a research hypothesis
- Definition of a research hypothesis
- The null hypothesis
What is a hypothesis?
Let’s start with the general definition of a hypothesis (not a research hypothesis or scientific hypothesis), according to the Cambridge Dictionary:
Hypothesis: an idea or explanation for something that is based on known facts but has not yet been proved.
In other words, it’s a statement that provides an explanation for why or how something works, based on facts (or some reasonable assumptions), but that has not yet been specifically tested . For example, a hypothesis might look something like this:
Hypothesis: sleep impacts academic performance.
This statement predicts that academic performance will be influenced by the amount and/or quality of sleep a student engages in – sounds reasonable, right? It’s based on reasonable assumptions , underpinned by what we currently know about sleep and health (from the existing literature). So, loosely speaking, we could call it a hypothesis, at least by the dictionary definition.
But that’s not good enough…
Unfortunately, that’s not quite sophisticated enough to describe a research hypothesis (also sometimes called a scientific hypothesis), and it wouldn’t be acceptable in a dissertation, thesis or research paper . In the world of academic research, a statement needs a few more criteria to constitute a true research hypothesis .
What is a research hypothesis?
A research hypothesis (also called a scientific hypothesis) is a statement about the expected outcome of a study (for example, a dissertation or thesis). To constitute a quality hypothesis, the statement needs to have three attributes – specificity , clarity and testability .
Let’s take a look at these more closely.
Need a helping hand?
Hypothesis Essential #1: Specificity & Clarity
A good research hypothesis needs to be extremely clear and articulate about both what’ s being assessed (who or what variables are involved ) and the expected outcome (for example, a difference between groups, a relationship between variables, etc.).
Let’s stick with our sleepy students example and look at how this statement could be more specific and clear.
Hypothesis: Students who sleep at least 8 hours per night will, on average, achieve higher grades in standardised tests than students who sleep less than 8 hours a night.
As you can see, the statement is very specific as it identifies the variables involved (sleep hours and test grades), the parties involved (two groups of students), as well as the predicted relationship type (a positive relationship). There’s no ambiguity or uncertainty about who or what is involved in the statement, and the expected outcome is clear.
Contrast that to the original hypothesis we looked at – “Sleep impacts academic performance” – and you can see the difference. “Sleep” and “academic performance” are both comparatively vague , and there’s no indication of what the expected relationship direction is (more sleep or less sleep). As you can see, specificity and clarity are key.
Hypothesis Essential #2: Testability (Provability)
A statement must be testable to qualify as a research hypothesis. In other words, there needs to be a way to prove (or disprove) the statement. If it’s not testable, it’s not a hypothesis – simple as that.
For example, consider the hypothesis we mentioned earlier:
We could test this statement by undertaking a quantitative study involving two groups of students, one that gets 8 or more hours of sleep per night for a fixed period, and one that gets less. We could then compare the standardised test results for both groups to see if there’s a statistically significant difference.
Again, if you compare this to the original hypothesis we looked at – “Sleep impacts academic performance” – you can see that it would be quite difficult to test that statement, primarily because it isn’t specific enough. How much sleep? By who? What type of academic performance?
So, remember the mantra – if you can’t test it, it’s not a hypothesis 🙂
Defining A Research Hypothesis
You’re still with us? Great! Let’s recap and pin down a clear definition of a hypothesis.
A research hypothesis (or scientific hypothesis) is a statement about an expected relationship between variables, or explanation of an occurrence, that is clear, specific and testable.
So, when you write up hypotheses for your dissertation or thesis, make sure that they meet all these criteria. If you do, you’ll not only have rock-solid hypotheses but you’ll also ensure a clear focus for your entire research project.
What about the null hypothesis?
You may have also heard the terms null hypothesis , alternative hypothesis, or H-zero thrown around. At a simple level, the null hypothesis is the counter-proposal to the original hypothesis.
For example, if the hypothesis predicts that there is a relationship between two variables (for example, sleep and academic performance), the null hypothesis would predict that there is no relationship between those variables.
At a more technical level, the null hypothesis proposes that no statistical significance exists in a set of given observations and that any differences are due to chance alone.
And there you have it – hypotheses in a nutshell.
If you have any questions, be sure to leave a comment below and we’ll do our best to help you. If you need hands-on help developing and testing your hypotheses, consider our private coaching service , where we hold your hand through the research journey.
Learn More About Methodology
How To Choose A Tutor For Your Dissertation
Hiring the right tutor for your dissertation or thesis can make the difference between passing and failing. Here’s what you need to consider.
5 Signs You Need A Dissertation Helper
Discover the 5 signs that suggest you need a dissertation helper to get unstuck, finish your degree and get your life back.
Triangulation: The Ultimate Credibility Enhancer
Triangulation is one of the best ways to enhance the credibility of your research. Learn about the different options here.
Research Limitations 101: What You Need To Know
Learn everything you need to know about research limitations (AKA limitations of the study). Includes practical examples from real studies.
In Vivo Coding 101: Full Explainer With Examples
Learn about in vivo coding, a popular qualitative coding technique ideal for studies where the nuances of language are central to the aims.
📄 FREE TEMPLATES
Research Topic Ideation
Proposal Writing
Literature Review
Methodology & Analysis
Academic Writing
Referencing & Citing
Apps, Tools & Tricks
The Grad Coach Podcast
18 Comments
Very useful information. I benefit more from getting more information in this regard.
Very great insight,educative and informative. Please give meet deep critics on many research data of public international Law like human rights, environment, natural resources, law of the sea etc
In a book I read a distinction is made between null, research, and alternative hypothesis. As far as I understand, alternative and research hypotheses are the same. Can you please elaborate? Best Afshin
This is a self explanatory, easy going site. I will recommend this to my friends and colleagues.
Very good definition. How can I cite your definition in my thesis? Thank you. Is nul hypothesis compulsory in a research?
It’s a counter-proposal to be proven as a rejection
Please what is the difference between alternate hypothesis and research hypothesis?
It is a very good explanation. However, it limits hypotheses to statistically tasteable ideas. What about for qualitative researches or other researches that involve quantitative data that don’t need statistical tests?
In qualitative research, one typically uses propositions, not hypotheses.
could you please elaborate it more
I’ve benefited greatly from these notes, thank you.
This is very helpful
well articulated ideas are presented here, thank you for being reliable sources of information
Excellent. Thanks for being clear and sound about the research methodology and hypothesis (quantitative research)
I have only a simple question regarding the null hypothesis. – Is the null hypothesis (Ho) known as the reversible hypothesis of the alternative hypothesis (H1? – How to test it in academic research?
Angelo Loye Very fantastic information. From here I am going straightaway to present the research hypothesis One question, do we apply hypothesis in qualitative research? What nul hypothesi Otherwise I appreciate your research methodo
this is very important note help me much more
Hi” best wishes to you and your very nice blog”
Trackbacks/Pingbacks
- What Is Research Methodology? Simple Definition (With Examples) - Grad Coach - […] Contrasted to this, a quantitative methodology is typically used when the research aims and objectives are confirmatory in nature. For example,…
Submit a Comment Cancel reply
Your email address will not be published. Required fields are marked *
Save my name, email, and website in this browser for the next time I comment.
Submit Comment
- Print Friendly
- Privacy Policy
Home » What is a Hypothesis – Types, Examples and Writing Guide
What is a Hypothesis – Types, Examples and Writing Guide
Table of Contents
In research, a hypothesis is a clear, testable statement predicting the relationship between variables or the outcome of a study. Hypotheses form the foundation of scientific inquiry, providing a direction for investigation and guiding the data collection and analysis process. Hypotheses are typically used in quantitative research but can also inform some qualitative studies by offering a preliminary assumption about the subject being explored.
A hypothesis is a specific, testable prediction or statement that suggests an expected relationship between variables in a study. It acts as a starting point, guiding researchers to examine whether their predictions hold true based on collected data. For a hypothesis to be useful, it must be clear, concise, and based on prior knowledge or theoretical frameworks.
Key Characteristics of a Hypothesis :
- Testable : Must be possible to evaluate or observe the outcome through experimentation or analysis.
- Specific : Clearly defines variables and the expected relationship or outcome.
- Predictive : States an anticipated effect or association that can be confirmed or refuted.
Example : “Increasing the amount of daily physical exercise will lead to a reduction in stress levels among college students.”
Types of Hypotheses
Hypotheses can be categorized into several types, depending on their structure, purpose, and the type of relationship they suggest. The most common types include null hypothesis , alternative hypothesis , directional hypothesis , and non-directional hypothesis .
1. Null Hypothesis (H₀)
Definition : The null hypothesis states that there is no relationship between the variables being studied or that any observed effect is due to chance. It serves as the default position, which researchers aim to test against to determine if a significant effect or association exists.
Purpose : To provide a baseline that can be statistically tested to verify if a relationship or difference exists.
Example : “There is no difference in academic performance between students who receive additional tutoring and those who do not.”
2. Alternative Hypothesis (H₁ or Hₐ)
Definition : The alternative hypothesis proposes that there is a relationship or effect between variables. This hypothesis contradicts the null hypothesis and suggests that any observed result is not due to chance.
Purpose : To present an expected outcome that researchers aim to support with data.
Example : “Students who receive additional tutoring will perform better academically than those who do not.”
3. Directional Hypothesis
Definition : A directional hypothesis specifies the direction of the expected relationship between variables, predicting either an increase, decrease, positive, or negative effect.
Purpose : To provide a more precise prediction by indicating the expected direction of the relationship.
Example : “Increasing the duration of daily exercise will lead to a decrease in stress levels among adults.”
4. Non-Directional Hypothesis
Definition : A non-directional hypothesis states that there is a relationship between variables but does not specify the direction of the effect.
Purpose : To allow for exploration of the relationship without committing to a particular direction.
Example : “There is a difference in stress levels between adults who exercise regularly and those who do not.”
Examples of Hypotheses in Different Fields
- Null Hypothesis : “There is no difference in anxiety levels between individuals who practice mindfulness and those who do not.”
- Alternative Hypothesis : “Individuals who practice mindfulness will report lower anxiety levels than those who do not.”
- Directional Hypothesis : “Providing feedback will improve students’ motivation to learn.”
- Non-Directional Hypothesis : “There is a difference in motivation levels between students who receive feedback and those who do not.”
- Null Hypothesis : “There is no association between diet and energy levels among teenagers.”
- Alternative Hypothesis : “A balanced diet is associated with higher energy levels among teenagers.”
- Directional Hypothesis : “An increase in employee engagement activities will lead to improved job satisfaction.”
- Non-Directional Hypothesis : “There is a relationship between employee engagement activities and job satisfaction.”
- Null Hypothesis : “The introduction of green spaces does not affect urban air quality.”
- Alternative Hypothesis : “Green spaces improve urban air quality.”
Writing Guide for Hypotheses
Writing a clear, testable hypothesis involves several steps, starting with understanding the research question and selecting variables. Here’s a step-by-step guide to writing an effective hypothesis.
Step 1: Identify the Research Question
Start by defining the primary research question you aim to investigate. This question should be focused, researchable, and specific enough to allow for hypothesis formation.
Example : “Does regular physical exercise improve mental well-being in college students?”
Step 2: Conduct Background Research
Review relevant literature to gain insight into existing theories, studies, and gaps in knowledge. This helps you understand prior findings and guides you in forming a logical hypothesis based on evidence.
Example : Research shows a positive correlation between exercise and mental well-being, which supports forming a hypothesis in this area.
Step 3: Define the Variables
Identify the independent and dependent variables. The independent variable is the factor you manipulate or consider as the cause, while the dependent variable is the outcome or effect you are measuring.
- Independent Variable : Amount of physical exercise
- Dependent Variable : Mental well-being (measured through self-reported stress levels)
Step 4: Choose the Hypothesis Type
Select the hypothesis type based on the research question. If you predict a specific outcome or direction, use a directional hypothesis. If not, a non-directional hypothesis may be suitable.
Example : “Increasing the frequency of physical exercise will reduce stress levels among college students” (directional hypothesis).
Step 5: Write the Hypothesis
Formulate the hypothesis as a clear, concise statement. Ensure it is specific, testable, and focuses on the relationship between the variables.
Example : “College students who exercise at least three times per week will report lower stress levels than those who do not exercise regularly.”
Step 6: Test and Refine (Optional)
In some cases, it may be necessary to refine the hypothesis after conducting a preliminary test or pilot study. This ensures that your hypothesis is realistic and feasible within the study parameters.
Tips for Writing an Effective Hypothesis
- Use Clear Language : Avoid jargon or ambiguous terms to ensure your hypothesis is easily understandable.
- Be Specific : Specify the expected relationship between the variables, and, if possible, include the direction of the effect.
- Ensure Testability : Frame the hypothesis in a way that allows for empirical testing or observation.
- Focus on One Relationship : Avoid complexity by focusing on a single, clear relationship between variables.
- Make It Measurable : Choose variables that can be quantified or observed to simplify data collection and analysis.
Common Mistakes to Avoid
- Vague Statements : Avoid vague hypotheses that don’t specify a clear relationship or outcome.
- Unmeasurable Variables : Ensure that the variables in your hypothesis can be observed, measured, or quantified.
- Overly Complex Hypotheses : Keep the hypothesis simple and focused, especially for beginner researchers.
- Using Personal Opinions : Avoid subjective or biased language that could impact the neutrality of the hypothesis.
Examples of Well-Written Hypotheses
- Psychology : “Adolescents who spend more than two hours on social media per day will report higher levels of anxiety than those who spend less than one hour.”
- Business : “Increasing customer service training will improve customer satisfaction ratings among retail employees.”
- Health : “Consuming a diet rich in fruits and vegetables is associated with lower cholesterol levels in adults.”
- Education : “Students who participate in active learning techniques will have higher retention rates compared to those in traditional lecture-based classrooms.”
- Environmental Science : “Urban areas with more green spaces will report lower average temperatures than those with minimal green coverage.”
A well-formulated hypothesis is essential to the research process, providing a clear and testable prediction about the relationship between variables. Understanding the different types of hypotheses, following a structured writing approach, and avoiding common pitfalls help researchers create hypotheses that effectively guide data collection, analysis, and conclusions. Whether working in psychology, education, health sciences, or any other field, an effective hypothesis sharpens the focus of a study and enhances the rigor of research.
- Creswell, J. W., & Creswell, J. D. (2018). Research Design: Qualitative, Quantitative, and Mixed Methods Approaches (5th ed.). SAGE Publications.
- Field, A. (2013). Discovering Statistics Using IBM SPSS Statistics (4th ed.). SAGE Publications.
- Trochim, W. M. K. (2006). The Research Methods Knowledge Base (3rd ed.). Atomic Dog Publishing.
- McLeod, S. A. (2019). What is a Hypothesis? Retrieved from https://www.simplypsychology.org/what-is-a-hypotheses.html
- Walliman, N. (2017). Research Methods: The Basics (2nd ed.). Routledge.
About the author
Muhammad Hassan
Researcher, Academic Writer, Web developer
You may also like
Survey Instruments – List and Their Uses
Appendix in Research Paper – Examples and...
Dissertation vs Thesis – Key Differences
Context of the Study – Writing Guide and Examples
Implications in Research – Types, Examples and...
Dissertation – Format, Example and Template
Have a language expert improve your writing
Run a free plagiarism check in 10 minutes, automatically generate references for free.
- Knowledge Base
- Methodology
- How to Write a Strong Hypothesis | Guide & Examples
How to Write a Strong Hypothesis | Guide & Examples
Published on 6 May 2022 by Shona McCombes .
A hypothesis is a statement that can be tested by scientific research. If you want to test a relationship between two or more variables, you need to write hypotheses before you start your experiment or data collection.
Table of contents
What is a hypothesis, developing a hypothesis (with example), hypothesis examples, frequently asked questions about writing hypotheses.
A hypothesis states your predictions about what your research will find. It is a tentative answer to your research question that has not yet been tested. For some research projects, you might have to write several hypotheses that address different aspects of your research question.
A hypothesis is not just a guess – it should be based on existing theories and knowledge. It also has to be testable, which means you can support or refute it through scientific research methods (such as experiments, observations, and statistical analysis of data).
Variables in hypotheses
Hypotheses propose a relationship between two or more variables . An independent variable is something the researcher changes or controls. A dependent variable is something the researcher observes and measures.
In this example, the independent variable is exposure to the sun – the assumed cause . The dependent variable is the level of happiness – the assumed effect .
Prevent plagiarism, run a free check.
Step 1: ask a question.
Writing a hypothesis begins with a research question that you want to answer. The question should be focused, specific, and researchable within the constraints of your project.
Step 2: Do some preliminary research
Your initial answer to the question should be based on what is already known about the topic. Look for theories and previous studies to help you form educated assumptions about what your research will find.
At this stage, you might construct a conceptual framework to identify which variables you will study and what you think the relationships are between them. Sometimes, you’ll have to operationalise more complex constructs.
Step 3: Formulate your hypothesis
Now you should have some idea of what you expect to find. Write your initial answer to the question in a clear, concise sentence.
Step 4: Refine your hypothesis
You need to make sure your hypothesis is specific and testable. There are various ways of phrasing a hypothesis, but all the terms you use should have clear definitions, and the hypothesis should contain:
- The relevant variables
- The specific group being studied
- The predicted outcome of the experiment or analysis
Step 5: Phrase your hypothesis in three ways
To identify the variables, you can write a simple prediction in if … then form. The first part of the sentence states the independent variable and the second part states the dependent variable.
In academic research, hypotheses are more commonly phrased in terms of correlations or effects, where you directly state the predicted relationship between variables.
If you are comparing two groups, the hypothesis can state what difference you expect to find between them.
Step 6. Write a null hypothesis
If your research involves statistical hypothesis testing , you will also have to write a null hypothesis. The null hypothesis is the default position that there is no association between the variables. The null hypothesis is written as H 0 , while the alternative hypothesis is H 1 or H a .
Hypothesis testing is a formal procedure for investigating our ideas about the world using statistics. It is used by scientists to test specific predictions, called hypotheses , by calculating how likely it is that a pattern or relationship between variables could have arisen by chance.
A hypothesis is not just a guess. It should be based on existing theories and knowledge. It also has to be testable, which means you can support or refute it through scientific research methods (such as experiments, observations, and statistical analysis of data).
A research hypothesis is your proposed answer to your research question. The research hypothesis usually includes an explanation (‘ x affects y because …’).
A statistical hypothesis, on the other hand, is a mathematical statement about a population parameter. Statistical hypotheses always come in pairs: the null and alternative hypotheses. In a well-designed study , the statistical hypotheses correspond logically to the research hypothesis.
Cite this Scribbr article
If you want to cite this source, you can copy and paste the citation or click the ‘Cite this Scribbr article’ button to automatically add the citation to our free Reference Generator.
McCombes, S. (2022, May 06). How to Write a Strong Hypothesis | Guide & Examples. Scribbr. Retrieved 11 November 2024, from https://www.scribbr.co.uk/research-methods/hypothesis-writing/
Is this article helpful?
Shona McCombes
Other students also liked, operationalisation | a guide with examples, pros & cons, what is a conceptual framework | tips & examples, a quick guide to experimental design | 5 steps & examples.
An official website of the United States government
Official websites use .gov A .gov website belongs to an official government organization in the United States.
Secure .gov websites use HTTPS A lock ( Lock Locked padlock icon ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.
- Publications
- Account settings
- Advanced Search
- Journal List
Scientific Hypotheses: Writing, Promoting, and Predicting Implications
Armen yuri gasparyan, lilit ayvazyan, ulzhan mukanova, marlen yessirkepov, george d kitas.
- Author information
- Article notes
- Copyright and License information
Address for Correspondence: Armen Yuri Gasparyan, MD. Departments of Rheumatology and Research and Development, Dudley Group NHS Foundation Trust (Teaching Trust of the University of Birmingham, UK), Russells Hall Hospital, Pensnett Road, Dudley, West Midlands DY1 2HQ, UK. [email protected]
Corresponding author.
Received 2019 Sep 2; Accepted 2019 Oct 28; Collection date 2019 Nov 25.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( https://creativecommons.org/licenses/by-nc/4.0/ ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Scientific hypotheses are essential for progress in rapidly developing academic disciplines. Proposing new ideas and hypotheses require thorough analyses of evidence-based data and predictions of the implications. One of the main concerns relates to the ethical implications of the generated hypotheses. The authors may need to outline potential benefits and limitations of their suggestions and target widely visible publication outlets to ignite discussion by experts and start testing the hypotheses. Not many publication outlets are currently welcoming hypotheses and unconventional ideas that may open gates to criticism and conservative remarks. A few scholarly journals guide the authors on how to structure hypotheses. Reflecting on general and specific issues around the subject matter is often recommended for drafting a well-structured hypothesis article. An analysis of influential hypotheses, presented in this article, particularly Strachan's hygiene hypothesis with global implications in the field of immunology and allergy, points to the need for properly interpreting and testing new suggestions. Envisaging the ethical implications of the hypotheses should be considered both by authors and journal editors during the writing and publishing process.
Keywords: Bibliographic Databases, Peer Review, Writing, Research Ethics, Hypothesis, Impact
INTRODUCTION
We live in times of digitization that radically changes scientific research, reporting, and publishing strategies. Researchers all over the world are overwhelmed with processing large volumes of information and searching through numerous online platforms, all of which make the whole process of scholarly analysis and synthesis complex and sophisticated.
Current research activities are diversifying to combine scientific observations with analysis of facts recorded by scholars from various professional backgrounds. 1 Citation analyses and networking on social media are also becoming essential for shaping research and publishing strategies globally. 2 Learning specifics of increasingly interdisciplinary research studies and acquiring information facilitation skills aid researchers in formulating innovative ideas and predicting developments in interrelated scientific fields.
Arguably, researchers are currently offered more opportunities than in the past for generating new ideas by performing their routine laboratory activities, observing individual cases and unusual developments, and critically analyzing published scientific facts. What they need at the start of their research is to formulate a scientific hypothesis that revisits conventional theories, real-world processes, and related evidence to propose new studies and test ideas in an ethical way. 3 Such a hypothesis can be of most benefit if published in an ethical journal with wide visibility and exposure to relevant online databases and promotion platforms.
Although hypotheses are crucially important for the scientific progress, only few highly skilled researchers formulate and eventually publish their innovative ideas per se . Understandably, in an increasingly competitive research environment, most authors would prefer to prioritize their ideas by discussing and conducting tests in their own laboratories or clinical departments, and publishing research reports afterwards. However, there are instances when simple observations and research studies in a single center are not capable of explaining and testing new groundbreaking ideas. Formulating hypothesis articles first and calling for multicenter and interdisciplinary research can be a solution in such instances, potentially launching influential scientific directions, if not academic disciplines.
The aim of this article is to overview the importance and implications of infrequently published scientific hypotheses that may open new avenues of thinking and research.
Despite the seemingly established views on innovative ideas and hypotheses as essential research tools, no structured definition exists to tag the term and systematically track related articles. In 1973, the Medical Subject Heading (MeSH) of the U.S. National Library of Medicine introduced “Research Design” as a structured keyword that referred to the importance of collecting data and properly testing hypotheses, and indirectly linked the term to ethics, methods and standards, among many other subheadings.
One of the experts in the field defines “hypothesis” as a well-argued analysis of available evidence to provide a realistic (scientific) explanation of existing facts, fill gaps in public understanding of sophisticated processes, and propose a new theory or a test. 4 A hypothesis can be proven wrong partially or entirely. However, even such an erroneous hypothesis may influence progress in science by initiating professional debates that help generate more realistic ideas. The main ethical requirement for hypothesis authors is to be honest about the limitations of their suggestions. 5
EXAMPLES OF INFLUENTIAL SCIENTIFIC HYPOTHESES
Daily routine in a research laboratory may lead to groundbreaking discoveries provided the daily accounts are comprehensively analyzed and reproduced by peers. The discovery of penicillin by Sir Alexander Fleming (1928) can be viewed as a prime example of such discoveries that introduced therapies to treat staphylococcal and streptococcal infections and modulate blood coagulation. 6 , 7 Penicillin got worldwide recognition due to the inventor's seminal works published by highly prestigious and widely visible British journals, effective ‘real-world’ antibiotic therapy of pneumonia and wounds during World War II, and euphoric media coverage. 8 In 1945, Fleming, Florey and Chain got a much deserved Nobel Prize in Physiology or Medicine for the discovery that led to the mass production of the wonder drug in the U.S. and ‘real-world practice’ that tested the use of penicillin. What remained globally unnoticed is that Zinaida Yermolyeva, the outstanding Soviet microbiologist, created the Soviet penicillin, which turned out to be more effective than the Anglo-American penicillin and entered mass production in 1943; that year marked the turning of the tide of the Great Patriotic War. 9 One of the reasons of the widely unnoticed discovery of Zinaida Yermolyeva is that her works were published exclusively by local Russian (Soviet) journals.
The past decades have been marked by an unprecedented growth of multicenter and global research studies involving hundreds and thousands of human subjects. This trend is shaped by an increasing number of reports on clinical trials and large cohort studies that create a strong evidence base for practice recommendations. Mega-studies may help generate and test large-scale hypotheses aiming to solve health issues globally. Properly designed epidemiological studies, for example, may introduce clarity to the hygiene hypothesis that was originally proposed by David Strachan in 1989. 10 David Strachan studied the epidemiology of hay fever in a cohort of 17,414 British children and concluded that declining family size and improved personal hygiene had reduced the chances of cross infections in families, resulting in epidemics of atopic disease in post-industrial Britain. Over the past four decades, several related hypotheses have been proposed to expand the potential role of symbiotic microorganisms and parasites in the development of human physiological immune responses early in life and protection from allergic and autoimmune diseases later on. 11 , 12 Given the popularity and the scientific importance of the hygiene hypothesis, it was introduced as a MeSH term in 2012. 13
Hypotheses can be proposed based on an analysis of recorded historic events that resulted in mass migrations and spreading of certain genetic diseases. As a prime example, familial Mediterranean fever (FMF), the prototype periodic fever syndrome, is believed to spread from Mesopotamia to the Mediterranean region and all over Europe due to migrations and religious prosecutions millennia ago. 14 Genetic mutations spearing mild clinical forms of FMF are hypothesized to emerge and persist in the Mediterranean region as protective factors against more serious infectious diseases, particularly tuberculosis, historically common in that part of the world. 15 The speculations over the advantages of carrying the MEditerranean FeVer (MEFV) gene are further strengthened by recorded low mortality rates from tuberculosis among FMF patients of different nationalities living in Tunisia in the first half of the 20th century. 16
Diagnostic hypotheses shedding light on peculiarities of diseases throughout the history of mankind can be formulated using artefacts, particularly historic paintings. 17 Such paintings may reveal joint deformities and disfigurements due to rheumatic diseases in individual subjects. A series of paintings with similar signs of pathological conditions interpreted in a historic context may uncover mysteries of epidemics of certain diseases, which is the case with Ruben's paintings depicting signs of rheumatic hands and making some doctors to believe that rheumatoid arthritis was common in Europe in the 16th and 17th century. 18
WRITING SCIENTIFIC HYPOTHESES
There are author instructions of a few journals that specifically guide how to structure, format, and make submissions categorized as hypotheses attractive. One of the examples is presented by Med Hypotheses , the flagship journal in its field with more than four decades of publishing and influencing hypothesis authors globally. However, such guidance is not based on widely discussed, implemented, and approved reporting standards, which are becoming mandatory for all scholarly journals.
Generating new ideas and scientific hypotheses is a sophisticated task since not all researchers and authors are skilled to plan, conduct, and interpret various research studies. Some experience with formulating focused research questions and strong working hypotheses of original research studies is definitely helpful for advancing critical appraisal skills. However, aspiring authors of scientific hypotheses may need something different, which is more related to discerning scientific facts, pooling homogenous data from primary research works, and synthesizing new information in a systematic way by analyzing similar sets of articles. To some extent, this activity is reminiscent of writing narrative and systematic reviews. As in the case of reviews, scientific hypotheses need to be formulated on the basis of comprehensive search strategies to retrieve all available studies on the topics of interest and then synthesize new information selectively referring to the most relevant items. One of the main differences between scientific hypothesis and review articles relates to the volume of supportive literature sources ( Table 1 ). In fact, hypothesis is usually formulated by referring to a few scientific facts or compelling evidence derived from a handful of literature sources. 19 By contrast, reviews require analyses of a large number of published documents retrieved from several well-organized and evidence-based databases in accordance with predefined search strategies. 20 , 21 , 22
Table 1. Characteristics of scientific hypotheses and narrative and systematic reviews.
The format of hypotheses, especially the implications part, may vary widely across disciplines. Clinicians may limit their suggestions to the clinical manifestations of diseases, outcomes, and management strategies. Basic and laboratory scientists analysing genetic, molecular, and biochemical mechanisms may need to view beyond the frames of their narrow fields and predict social and population-based implications of the proposed ideas. 23
Advanced writing skills are essential for presenting an interesting theoretical article which appeals to the global readership. Merely listing opposing facts and ideas, without proper interpretation and analysis, may distract the experienced readers. The essence of a great hypothesis is a story behind the scientific facts and evidence-based data.
ETHICAL IMPLICATIONS
The authors of hypotheses substantiate their arguments by referring to and discerning rational points from published articles that might be overlooked by others. Their arguments may contradict the established theories and practices, and pose global ethical issues, particularly when more or less efficient medical technologies and public health interventions are devalued. The ethical issues may arise primarily because of the careless references to articles with low priorities, inadequate and apparently unethical methodologies, and concealed reporting of negative results. 24 , 25
Misinterpretation and misunderstanding of the published ideas and scientific hypotheses may complicate the issue further. For example, Alexander Fleming, whose innovative ideas of penicillin use to kill susceptible bacteria saved millions of lives, warned of the consequences of uncontrolled prescription of the drug. The issue of antibiotic resistance had emerged within the first ten years of penicillin use on a global scale due to the overprescription that affected the efficacy of antibiotic therapies, with undesirable consequences for millions. 26
The misunderstanding of the hygiene hypothesis that primarily aimed to shed light on the role of the microbiome in allergic and autoimmune diseases resulted in decline of public confidence in hygiene with dire societal implications, forcing some experts to abandon the original idea. 27 , 28 Although that hypothesis is unrelated to the issue of vaccinations, the public misunderstanding has resulted in decline of vaccinations at a time of upsurge of old and new infections.
A number of ethical issues are posed by the denial of the viral (human immunodeficiency viruses; HIV) hypothesis of acquired Immune deficiency Syndrome (AIDS) by Peter Duesberg, who overviewed the links between illicit recreational drugs and antiretroviral therapies with AIDS and refuted the etiological role of HIV. 29 That controversial hypothesis was rejected by several journals, but was eventually published without external peer review at Med Hypotheses in 2010. The publication itself raised concerns of the unconventional editorial policy of the journal, causing major perturbations and more scrutinized publishing policies by journals processing hypotheses.
WHERE TO PUBLISH HYPOTHESES
Although scientific authors are currently well informed and equipped with search tools to draft evidence-based hypotheses, there are still limited quality publication outlets calling for related articles. The journal editors may be hesitant to publish articles that do not adhere to any research reporting guidelines and open gates for harsh criticism of unconventional and untested ideas. Occasionally, the editors opting for open-access publishing and upgrading their ethics regulations launch a section to selectively publish scientific hypotheses attractive to the experienced readers. 30 However, the absence of approved standards for this article type, particularly no mandate for outlining potential ethical implications, may lead to publication of potentially harmful ideas in an attractive format.
A suggestion of simultaneously publishing multiple or alternative hypotheses to balance the reader views and feedback is a potential solution for the mainstream scholarly journals. 31 However, that option alone is hardly applicable to emerging journals with unconventional quality checks and peer review, accumulating papers with multiple rejections by established journals.
A large group of experts view hypotheses with improbable and controversial ideas publishable after formal editorial (in-house) checks to preserve the authors' genuine ideas and avoid conservative amendments imposed by external peer reviewers. 32 That approach may be acceptable for established publishers with large teams of experienced editors. However, the same approach can lead to dire consequences if employed by nonselective start-up, open-access journals processing all types of articles and primarily accepting those with charged publication fees. 33 In fact, pseudoscientific ideas arguing Newton's and Einstein's seminal works or those denying climate change that are hardly testable have already found their niche in substandard electronic journals with soft or nonexistent peer review. 34
CITATIONS AND SOCIAL MEDIA ATTENTION
The available preliminary evidence points to the attractiveness of hypothesis articles for readers, particularly those from research-intensive countries who actively download related documents. 35 However, citations of such articles are disproportionately low. Only a small proportion of top-downloaded hypotheses (13%) in the highly prestigious Med Hypotheses receive on average 5 citations per article within a two-year window. 36
With the exception of a few historic papers, the vast majority of hypotheses attract relatively small number of citations in a long term. 36 Plausible explanations are that these articles often contain a single or only a few citable points and that suggested research studies to test hypotheses are rarely conducted and reported, limiting chances of citing and crediting authors of genuine research ideas.
A snapshot analysis of citation activity of hypothesis articles may reveal interest of the global scientific community towards their implications across various disciplines and countries. As a prime example, Strachan's hygiene hypothesis, published in 1989, 10 is still attracting numerous citations on Scopus, the largest bibliographic database. As of August 28, 2019, the number of the linked citations in the database is 3,201. Of the citing articles, 160 are cited at least 160 times ( h -index of this research topic = 160). The first three citations are recorded in 1992 and followed by a rapid annual increase in citation activity and a peak of 212 in 2015 ( Fig. 1 ). The top 5 sources of the citations are Clin Exp Allergy (n = 136), J Allergy Clin Immunol (n = 119), Allergy (n = 81), Pediatr Allergy Immunol (n = 69), and PLOS One (n = 44). The top 5 citing authors are leading experts in pediatrics and allergology Erika von Mutius (Munich, Germany, number of publications with the index citation = 30), Erika Isolauri (Turku, Finland, n = 27), Patrick G Holt (Subiaco, Australia, n = 25), David P. Strachan (London, UK, n = 23), and Bengt Björksten (Stockholm, Sweden, n = 22). The U.S. is the leading country in terms of citation activity with 809 related documents, followed by the UK (n = 494), Germany (n = 314), Australia (n = 211), and the Netherlands (n = 177). The largest proportion of citing documents are articles (n = 1,726, 54%), followed by reviews (n = 950, 29.7%), and book chapters (n = 213, 6.7%). The main subject areas of the citing items are medicine (n = 2,581, 51.7%), immunology and microbiology (n = 1,179, 23.6%), and biochemistry, genetics and molecular biology (n = 415, 8.3%).
Fig. 1. Number of Scopus-indexed items citing Strachan's hygiene hypothesis in 1992–2019 (as of August 28, 2019).
Interestingly, a recent analysis of 111 publications related to Strachan's hygiene hypothesis, stating that the lack of exposure to infections in early life increases the risk of rhinitis, revealed a selection bias of 5,551 citations on Web of Science. 37 The articles supportive of the hypothesis were cited more than nonsupportive ones (odds ratio adjusted for study design, 2.2; 95% confidence interval, 1.6–3.1). A similar conclusion pointing to a citation bias distorting bibliometrics of hypotheses was reached by an earlier analysis of a citation network linked to the idea that β-amyloid, which is involved in the pathogenesis of Alzheimer disease, is produced by skeletal muscle of patients with inclusion body myositis. 38 The results of both studies are in line with the notion that ‘positive’ citations are more frequent in the field of biomedicine than ‘negative’ ones, and that citations to articles with proven hypotheses are too common. 39
Social media channels are playing an increasingly active role in the generation and evaluation of scientific hypotheses. In fact, publicly discussing research questions on platforms of news outlets, such as Reddit, may shape hypotheses on health-related issues of global importance, such as obesity. 40 Analyzing Twitter comments, researchers may reveal both potentially valuable ideas and unfounded claims that surround groundbreaking research ideas. 41 Social media activities, however, are unevenly distributed across different research topics, journals and countries, and these are not always objective professional reflections of the breakthroughs in science. 2 , 42
Scientific hypotheses are essential for progress in science and advances in healthcare. Innovative ideas should be based on a critical overview of related scientific facts and evidence-based data, often overlooked by others. To generate realistic hypothetical theories, the authors should comprehensively analyze the literature and suggest relevant and ethically sound design for future studies. They should also consider their hypotheses in the context of research and publication ethics norms acceptable for their target journals. The journal editors aiming to diversify their portfolio by maintaining and introducing hypotheses section are in a position to upgrade guidelines for related articles by pointing to general and specific analyses of the subject, preferred study designs to test hypotheses, and ethical implications. The latter is closely related to specifics of hypotheses. For example, editorial recommendations to outline benefits and risks of a new laboratory test or therapy may result in a more balanced article and minimize associated risks afterwards.
Not all scientific hypotheses have immediate positive effects. Some, if not most, are never tested in properly designed research studies and never cited in credible and indexed publication outlets. Hypotheses in specialized scientific fields, particularly those hardly understandable for nonexperts, lose their attractiveness for increasingly interdisciplinary audience. The authors' honest analysis of the benefits and limitations of their hypotheses and concerted efforts of all stakeholders in science communication to initiate public discussion on widely visible platforms and social media may reveal rational points and caveats of the new ideas.
Disclosure: The authors have no potential conflicts of interest to disclose.
- Conceptualization: Gasparyan AY, Yessirkepov M, Kitas GD.
- Methodology: Gasparyan AY, Mukanova U, Ayvazyan L.
- Writing - original draft: Gasparyan AY, Ayvazyan L, Yessirkepov M.
- Writing - review & editing: Gasparyan AY, Yessirkepov M, Mukanova U, Kitas GD.
- 1. O'Shea P. Future medicine shaped by an interdisciplinary new biology. Lancet. 2012;379(9825):1544–1550. doi: 10.1016/S0140-6736(12)60476-0. [ DOI ] [ PubMed ] [ Google Scholar ]
- 2. Kolahi J, Khazaei S, Iranmanesh P, Soltani P. Analysis of highly tweeted dental journals and articles: a science mapping approach. Br Dent J. 2019;226(9):673–678. doi: 10.1038/s41415-019-0212-z. [ DOI ] [ PubMed ] [ Google Scholar ]
- 3. Heidary F, Gharebaghi R. Surgical innovation, a niche and a need. Med Hypothesis Discov Innov Ophthalmol. 2012;1(4):65–66. [ PMC free article ] [ PubMed ] [ Google Scholar ]
- 4. Bains W. Hypotheses, limits, models and life. Life (Basel) 2014;5(1):1–3. doi: 10.3390/life5010001. [ DOI ] [ PMC free article ] [ PubMed ] [ Google Scholar ]
- 5. Bains W. Hypotheses and humility: Ideas do not have to be right to be useful. Biosci Hypotheses. 2009;2(1):1–2. [ Google Scholar ]
- 6. Fleming A, Fish EW. Influence of penicillin on the coagulation of blood with especial reference to certain dental operations. BMJ. 1947;2(4519):242–243. doi: 10.1136/bmj.2.4519.242. [ DOI ] [ PMC free article ] [ PubMed ] [ Google Scholar ]
- 7. Bentley R. The development of penicillin: genesis of a famous antibiotic. Perspect Biol Med. 2005;48(3):444–452. doi: 10.1353/pbm.2005.0068. [ DOI ] [ PubMed ] [ Google Scholar ]
- 8. Shama G. The role of the media in influencing public attitudes to penicillin during World War II. Dynamis. 2015;35(1):131–152. doi: 10.4321/s0211-95362015000100006. [ DOI ] [ PubMed ] [ Google Scholar ]
- 9. The appearance of penicillin. Antibiotics killers. [Accessed August 28, 2019]. https://btvar.ru/en/faringit/the-appearance-of-penicillin-antibioticskillers.html .
- 10. Strachan DP. Hay fever, hygiene, and household size. BMJ. 1989;299(6710):1259–1260. doi: 10.1136/bmj.299.6710.1259. [ DOI ] [ PMC free article ] [ PubMed ] [ Google Scholar ]
- 11. Bach JF. The effect of infections on susceptibility to autoimmune and allergic diseases. N Engl J Med. 2002;347(12):911–920. doi: 10.1056/NEJMra020100. [ DOI ] [ PubMed ] [ Google Scholar ]
- 12. Bach JF. The hygiene hypothesis in autoimmunity: the role of pathogens and commensals. Nat Rev Immunol. 2018;18(2):105–120. doi: 10.1038/nri.2017.111. [ DOI ] [ PubMed ] [ Google Scholar ]
- 13. Hygiene hypothesis. [Accessed August 28, 2019]. https://www.ncbi.nlm.nih.gov/mesh/?term=hygiene+hypothesis .
- 14. Ben-Chetrit E, Levy M. Familial Mediterranean fever. Lancet. 1998;351(9103):659–664. doi: 10.1016/S0140-6736(97)09408-7. [ DOI ] [ PubMed ] [ Google Scholar ]
- 15. Ozen S, Balci B, Ozkara S, Ozcan A, Yilmaz E, Besbas N, et al. Is there a heterozygote advantage for familial Mediterranean fever carriers against tuberculosis infections: speculations remain? Clin Exp Rheumatol. 2002;20(4) Suppl 26:S57–S58. [ PubMed ] [ Google Scholar ]
- 16. Cattan D. Familial Mediterranean fever: is low mortality from tuberculosis a specific advantage for MEFV mutations carriers? Mortality from tuberculosis among Muslims, Jewish, French, Italian and Maltese patients in Tunis (Tunisia) in the first half of the 20th century. Clin Exp Rheumatol. 2003;21(4) Suppl 30:S53–S54. [ PubMed ] [ Google Scholar ]
- 17. Chatzidionysiou K. Rheumatic disease and artistic creativity. Mediterr J Rheumatol. 2019;30(2):103–109. doi: 10.31138/mjr.30.2.103. [ DOI ] [ PMC free article ] [ PubMed ] [ Google Scholar ]
- 18. Appelboom T. Hypothesis: Rubens--one of the first victims of an epidemic of rheumatoid arthritis that started in the 16th-17th century? Rheumatology (Oxford) 2005;44(5):681–683. doi: 10.1093/rheumatology/keh252. [ DOI ] [ PubMed ] [ Google Scholar ]
- 19. Wardle J, Rossi V. Medical hypotheses: a clinician's guide to publication. Adv Intern Med. 2016;3(1):37–40. [ Google Scholar ]
- 20. Gasparyan AY, Ayvazyan L, Blackmore H, Kitas GD. Writing a narrative biomedical review: considerations for authors, peer reviewers, and editors. Rheumatol Int. 2011;31(11):1409–1417. doi: 10.1007/s00296-011-1999-3. [ DOI ] [ PubMed ] [ Google Scholar ]
- 21. Methley AM, Campbell S, Chew-Graham C, McNally R, Cheraghi-Sohi S. PICO, PICOS and SPIDER: a comparison study of specificity and sensitivity in three search tools for qualitative systematic reviews. BMC Health Serv Res. 2014;14(1):579. doi: 10.1186/s12913-014-0579-0. [ DOI ] [ PMC free article ] [ PubMed ] [ Google Scholar ]
- 22. Misra DP, Agarwal V. Systematic reviews: challenges for their justification, related comprehensive searches, and implications. J Korean Med Sci. 2018;33(12):e92. doi: 10.3346/jkms.2018.33.e92. [ DOI ] [ PMC free article ] [ PubMed ] [ Google Scholar ]
- 23. Heidary F, Gharebaghi R. Welcome to beautiful mind; a call to action. Med Hypothesis Discov Innov Ophthalmol. 2012;1(1):1–2. [ PMC free article ] [ PubMed ] [ Google Scholar ]
- 24. Erren TC, Shaw DM, Groß JV. How to avoid haste and waste in occupational, environmental and public health research. J Epidemiol Community Health. 2015;69(9):823–825. doi: 10.1136/jech-2015-205543. [ DOI ] [ PubMed ] [ Google Scholar ]
- 25. Ruxton GD, Mulder T. Unethical work must be filtered out or flagged. Nature. 2019;572(7768):171–172. doi: 10.1038/d41586-019-02378-x. [ DOI ] [ PubMed ] [ Google Scholar ]
- 26. Rosenblatt-Farrell N. The landscape of antibiotic resistance. Environ Health Perspect. 2009;117(6):A244–50. doi: 10.1289/ehp.117-a244. [ DOI ] [ PMC free article ] [ PubMed ] [ Google Scholar ]
- 27. Patki A. Eat dirt and avoid atopy: the hygiene hypothesis revisited. Indian J Dermatol Venereol Leprol. 2007;73(1):2–4. doi: 10.4103/0378-6323.30642. [ DOI ] [ PubMed ] [ Google Scholar ]
- 28. Bloomfield SF, Rook GA, Scott EA, Shanahan F, Stanwell-Smith R, Turner P. Time to abandon the hygiene hypothesis: new perspectives on allergic disease, the human microbiome, infectious disease prevention and the role of targeted hygiene. Perspect Public Health. 2016;136(4):213–224. doi: 10.1177/1757913916650225. [ DOI ] [ PMC free article ] [ PubMed ] [ Google Scholar ]
- 29. Goodson P. Questioning the HIV-AIDS hypothesis: 30 years of dissent. Front Public Health. 2014;2:154. doi: 10.3389/fpubh.2014.00154. [ DOI ] [ PMC free article ] [ PubMed ] [ Google Scholar ] [ Retracted ]
- 30. Abatzopoulos TJ. A new era for Journal of Biological Research-Thessaloniki . J Biol Res (Thessalon) 2014;21(1):1. doi: 10.1186/2241-5793-21-1. [ DOI ] [ PMC free article ] [ PubMed ] [ Google Scholar ]
- 31. Rosen J. Research protocols: a forest of hypotheses. Nature. 2016;536(7615):239–241. doi: 10.1038/nj7615-239a. [ DOI ] [ PubMed ] [ Google Scholar ]
- 32. Steinhauser G, Adlassnig W, Risch JA, Anderlini S, Arguriou P, Armendariz AZ, et al. Peer review versus editorial review and their role in innovative science. Theor Med Bioeth. 2012;33(5):359–376. doi: 10.1007/s11017-012-9233-1. [ DOI ] [ PubMed ] [ Google Scholar ]
- 33. Eriksson S, Helgesson G. The false academy: predatory publishing in science and bioethics. Med Health Care Philos. 2017;20(2):163–170. doi: 10.1007/s11019-016-9740-3. [ DOI ] [ PMC free article ] [ PubMed ] [ Google Scholar ]
- 34. Beall J. Dangerous predatory publishers threaten medical research. J Korean Med Sci. 2016;31(10):1511–1513. doi: 10.3346/jkms.2016.31.10.1511. [ DOI ] [ PMC free article ] [ PubMed ] [ Google Scholar ]
- 35. Bazrafshan A, Haghdoost AA, Zare M. A comparison of downloads, readership and citations data for the Journal of Medical Hypotheses and Ideas . J Med Hypotheses Ideas. 2015;9(1):1–4. [ Google Scholar ]
- 36. Zavos C, Kountouras J, Zavos N, Paspatis GA, Kouroumalis EA. Predicting future citations of a research paper from number of its internet downloads: the Medical Hypotheses case. Med Hypotheses. 2008;70(2):460–461. doi: 10.1016/j.mehy.2007.06.001. [ DOI ] [ PubMed ] [ Google Scholar ]
- 37. Duyx B, Urlings MJ, Swaen GM, Bouter LM, Zeegers MP. Selective citation in the literature on the hygiene hypothesis: a citation analysis on the association between infections and rhinitis. BMJ Open. 2019;9(2):e026518. doi: 10.1136/bmjopen-2018-026518. [ DOI ] [ PMC free article ] [ PubMed ] [ Google Scholar ]
- 38. Greenberg SA. How citation distortions create unfounded authority: analysis of a citation network. BMJ. 2009;339:b2680. doi: 10.1136/bmj.b2680. [ DOI ] [ PMC free article ] [ PubMed ] [ Google Scholar ]
- 39. Duyx B, Urlings MJ, Swaen GM, Bouter LM, Zeegers MP. Scientific citations favor positive results: a systematic review and meta-analysis. J Clin Epidemiol. 2017;88:92–101. doi: 10.1016/j.jclinepi.2017.06.002. [ DOI ] [ PubMed ] [ Google Scholar ]
- 40. Bevelander KE, Kaipainen K, Swain R, Dohle S, Bongard JC, Hines PD, et al. Crowdsourcing novel childhood predictors of adult obesity. PLoS One. 2014;9(2):e87756. doi: 10.1371/journal.pone.0087756. [ DOI ] [ PMC free article ] [ PubMed ] [ Google Scholar ]
- 41. Castelvecchi D. Physicists doubt bold superconductivity claim following social-media storm. Nature. 2018;560(7720):539–540. doi: 10.1038/d41586-018-06023-x. [ DOI ] [ PubMed ] [ Google Scholar ]
- 42. Kolahi J, Khazaei S. Altmetric analysis of contemporary dental literature. Br Dent J. 2018;225(1):68–72. doi: 10.1038/sj.bdj.2018.521. [ DOI ] [ PubMed ] [ Google Scholar ]
- View on publisher site
- PDF (955.6 KB)
- Collections
Similar articles
Cited by other articles, links to ncbi databases.
- Download .nbib .nbib
- Format: AMA APA MLA NLM
Add to Collections
Published November 23, 2021. Updated December 13, 2021.
A hypothesis is a testable statement based on the researcher’s expectation for the outcome of a study or an observed phenomenon. It helps establish a relationship between two or more variables. A hypothesis acts as the objective of research and guides the researcher to structure experiments that would produce accurate and reliable results. In all likelihood, if a hypothesis is proven by repeatable and reproducible experiments, it may become a theory or even a law of nature.
What is a hypothesis?
A research hypothesis is an educated, clear, specific and falsifiable prediction of the possible outcomes of scientific observation. A hypothesis can be considered as the starting point of research, as any research without it is aimless. For a hypothesis to be complete, it should contain three main elements, i.e., two or more variables, a population, and the correlation between the variables. A hypothesis lays out a path for researchers, directing them how exactly the experiment should be designed, the type of data that should be collected, the sample size for the experiment, and how the data analysis should be performed, along with providing a basis to obtain results and validate them.
Observation and prior knowledge are the primary steps to developing a research hypothesis. For example:
You are watching a race in school and observe the speed with which the winner ran. You may wonder why the winner ran so fast. You may think of a few possibilities which could lead to this result, such as the amount of practice before the race, hours of sleep, or consumption of an energy drink. Since the amount of practice and sleep may almost be constant for all the participants, you may feel the win is because of the consumption of an energy drink. So, you may develop a hypothesis such as “Athletes consuming an energy drink daily perform better.”
Developing a good hypothesis
A hypothesis is important as it helps predict the relationship between two variables, which is essential for conducting your research. In the previous example, the researcher uses the consumption of energy drinks and athlete performance as variables and the athletes as a population while trying to establish the effect of the consumption of an energy drink on the performance of an athlete.
A good hypothesis is central to research for providing reliable and valid results. There are a few points should be kept in mind while formulating your hypothesis. Let’s have a look at them.
1) Ask a question : The foremost step to developing a hypothesis is asking a question. Identifying a question which you are interested in studying is important. For example:
How can air pollution in a region be reduced?
2) Conceptual nature : A hypothesis should be related to a certain concept. This allows the linking of research questions in a study, collecting data, and performing analysis according to the stated concept. For example:
Regions with a greater percentage of tree cover are likely to be less polluted than regions with lower tree cover.
3) Verbal statement : A hypothesis is phrased as a declaration and never as a question. It is the representation of the researcher’s idea or assumption in words that can be tested. For example:
Bad hypothesis: Does following a healthy diet alter the weight of a person?
Good hypothesis: People who follow a healthy diet stay fit.
4) Falsifiable and testable : A hypothesis should be testable so that experiments can be conducted to make observations that agree or disagree with it. It should be falsifiable so that it can be proven wrong if it is found to be incorrect. For example:
Children who use phones while studying score low marks in their exams.
5) Relationship between two variables : A hypothesis suggests a relationship between two or more variables. An independent variable is controlled by the researcher to look at the effects on other variables, i.e., it is the cause for something to happen. A dependent variable is affected by the independent variable and is observed and measured by the researcher. For example:
Consumption of aerated drinks leads to increased blood sugar levels.
Here, the consumption of aerated drinks is the independent variable. The dependent variable is the sugar level that is affected by the consumption of aerated drinks.
6) Specific and precise : A hypothesis should not be too general or vague as obtaining focused results becomes difficult. Also, a hypothesis should not be too specific as it limits the scope of the study. For example:
General: Eating food leads to weight gain.
Specific: Eating ice cream causes weight gain.
Good hypothesis: Consumption of sugar-rich food causes weight in individuals.
If these factors are paid attention to while structuring your hypothesis, you are sure to formulate a sound hypothesis that will direct your research down the correct path.
Types of hypotheses
The hypothesis can be classified into the following categories:
1) Simple Hypothesis : Simple hypotheses draw a relationship between a single independent variable and a single dependent variable. For example:
Increased hours of studying by students leads to them getting better marks.
Here, the hours of study acts as the independent variable while the obtained marks act as the dependent variable.
2) Complex Hypothesis : A complex hypothesis tends to propose a relationship between two or more independent and dependent variables. For example:
Increased hours of studying and eight hours of sleep by students result in getting better marks by an increased attention span.
3) Directional Hypothesis : This type of hypothesis predicts the nature of the effect of an independent variable on the dependent variable, thus predicting the direction of the effect. For example:
Students scoring good marks in exams tend to have better jobs than the students who score low marks in exams.
Here both the effect and the direction of the effect are represented in the hypothesis.
4) Non-directional Hypothesis : The null hypothesis states a relationship between two variables but does not state the kind of effect that may exist between them. For example:
Students scoring good marks will have jobs different from students scoring low marks.
5) Null Hypothesis : This is a negative statement contrary to the hypothesis and suggests no relationship between the independent and the dependent variable. It is represented as H o . For example:
H o : There is no relationship between hours of study by a student and the earned marks.
H o : Students scoring good and low marks are likely to get similar jobs.
6) Alternative Hypothesis : An alternative to the null hypothesis, it suggests the difference or effect between two or more variables. It is represented as H 1 . For example:
H 1 : There is a relationship between hours of study by a student and the earned marks.
H 1 : Students scoring good and low marks are likely to get different quality jobs.
How to structure a hypothesis?
A hypothesis should be structured in such a way that it should be simple, clear, and easy to understand, and should represent the intent of the hypothesis. There are a few ways to do this:
1) A hypothesis can be represented as a simple ‘if…then’ statement. While the first part of the statement introduces the independent variable, the latter part brings up the dependent variable. For example:
If the plant is watered, then the plant’s growth will improve.
2) A hypothesis can also be written as a statement correlating two variables, directly predicting the relationship between the two variables. For example:
The more times a plant is watered, the better the growth of the plant will be.
3) Another way of structuring a hypothesis is to compare two groups and state the difference expected to occur between the two groups. For example:
Plants that are watered daily are taller than plants that are watered on alternate days.
Testing a hypothesis
Once you have formulated your hypothesis, the next step is to test it to determine if it is correct or incorrect. The steps given below help to test a hypothesis:
1) State your research hypothesis in the form of a null hypothesis (H o ) and an alternative hypothesis (H 1 ).
2) Perform appropriate experiments and collect data to test the hypothesis.
3) Analyze the data to see whether the hypothesis is supported or refuted.
4) Interpret the data and present your results.
Key takeaways
- A hypothesis is a testable statement based on the researcher’s expectation of an outcome for observed phenomena that is simple, clear, specific, and focuses on only one issue.
- A hypothesis is the focal point of research and directs the course of the research in terms of data collection, sample size, and data analysis.
- A hypothesis is composed of three main components: two or more variables, a population, and the relationship between the variables. Independent and dependent variables are two kinds of variables used while structuring a hypothesis.
- It should be possible to test the hypothesis by performing experiments and prove it to be correct or incorrect.
- A hypothesis helps in testing theories, investigating activities, explaining social phenomena. Further, while acting as a bridge between theory and investigation, it helps determine the most suitable type of research for a problem and allows for the empirical testing of a relationship between variables. If you are lucky, one of your hypotheses may suggest a theory!
Research Process
For more details, visit these additional research guides .
Understand the Research Process
- Research process
- Research questions
- Operationalization
- Research problem
- Statement of the problem
- Background research
- Research hypothesis
- Generalization
What’s included with a Chegg Writing subscription
- Unlimited number of paper scans
- Plagiarism detection: Check against billions of sources
- Expert proofreading for papers on any subject
- Grammar scans for 200+ types of common errors
- Automatically create & save citations in 7,000+ styles
- Cancel subscription anytime, no obligation
IMAGES
COMMENTS
5. Phrase your hypothesis in three ways. To identify the variables, you can write a simple prediction in if…then form. The first part of the sentence states the independent variable and the second part states the dependent variable. If a first-year student starts attending more lectures, then their exam scores will improve.
A hypothesis is a tentative statement about the relationship between two or more variables. It is a specific, testable prediction about what you expect to happen in a study. It is a preliminary answer to your question that helps guide the research process. Consider a study designed to examine the relationship between sleep deprivation and test ...
A research hypothesis (also called a scientific hypothesis) is a statement about the expected outcome of a study (for example, a dissertation or thesis). To constitute a quality hypothesis, the statement needs to have three attributes – specificity, clarity and testability. Let’s take a look at these more closely.
In research, a hypothesis is a clear, testable statement predicting the relationship between variables or the outcome of a study. Hypotheses form the foundation of scientific inquiry, providing a direction for investigation and guiding the data collection and analysis process.
The hypothesis is a tentative prediction of the nature and direction of relationships between sets of data, phrased as a declarative statement. Therefore, hypotheses are really only required for studies that address relational or causal research questions.
Claims are instead based on reasoning or deduction, but lack actual data. Examples: An alien raised on Venus would have trouble breathing in Earth’s atmosphere. Dinosaurs with sharp, pointed teeth were probably carnivores. 6 Empirical hypothesis. An empirical hypothesis, also known as a “working hypothesis,” is one that is currently being ...
Simple hypothesis. A simple hypothesis is a statement made to reflect the relation between exactly two variables. One independent and one dependent. Consider the example, “Smoking is a prominent cause of lung cancer." The dependent variable, lung cancer, is dependent on the independent variable, smoking. 4.
Step 5: Phrase your hypothesis in three ways. To identify the variables, you can write a simple prediction in if … then form. The first part of the sentence states the independent variable and the second part states the dependent variable. If a first-year student starts attending more lectures, then their exam scores will improve.
Scientific hypotheses are essential for progress in rapidly developing academic disciplines. Proposing new ideas and hypotheses require thorough analyses of evidence-based data and predictions of the implications. One of the main concerns relates to the ethical implications of the generated hypotheses. The authors may need to outline potential ...
A hypothesis is the focal point of research and directs the course of the research in terms of data collection, sample size, and data analysis. A hypothesis is composed of three main components: two or more variables, a population, and the relationship between the variables. Independent and dependent variables are two kinds of variables used ...